INITIAL DIAGNOSTIC ERRORS IN CHILDREN SUSPECTED OF HAVING HEART DISEASE: PREVALENCE AND LONG-TERM CONSEQUENCES

Initial diagnostic errors in children suspected of having heart disease: prevalence and long-term consequences

OBJECTIVE: To access the incidence of diagnostic errors in the initial evaluation of children with cardiac murmurs.METHODS: We evaluated our 7-years of experience in a public pediatric cardiology outpatient clinic.Of 3692 patients who were sent to the hospital, 2603 presented with a heart murmur and were investigated.Patients for whom a disagreemen

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Exposure to Hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni

Schistosoma mansoni is a parasitic plathyhelminth responsible for intestinal schistosomiasis (or bilharziasis), a disease affecting 67 million people worldwide and causing an important economic burden.The schistosomicides hycanthone, and its later proxy oxamniquine, were widely used for treatments in endemic areas during the 20th century.Recently,

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